Novel considerations on drug safety in epilepsy
نویسندگان
چکیده
منابع مشابه
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Drug resistance is a feature of different forms of epilepsy or epileptic syndromes. It is defined as the persistence of unacceptable seizures despite reasonable pharmacotherapy and drug use to the highest tolerable dosage. It affects between 20% and 30% of patients with epilepsy overall (1). In subgroups of epilepsy patients, a particularly high incidence of drug resistance is encountered (e.g....
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The development of resistance to pharmacological treatment is common to many human diseases. In chronic epilepsy, many patients develop resistance to anticonvulsant drug treatment during the course of their disease, with the underlying mechanisms remaining unclear. We have studied cellular mechanisms underlying drug resistance in resected hippocampal tissue from patients with temporal lobe epil...
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ژورنال
عنوان ژورنال: Expert Opinion on Drug Safety
سال: 2020
ISSN: 1474-0338,1744-764X
DOI: 10.1080/14740338.2021.1865913